2-FMC

Chemical Name: 2-fluoromethcathinone (2-FMC)
Systematic IUPAC Name: 2-fluoro-N-methylcathinone
CAS Number: N/A
ChemSpider Number: N/A
Molecular Formula: C10H12FNO
Molecular Mass: 181.206 g/mol

Acetildenafil

Acetildenafil (hongdenafil) is a drug which acts as a phosphodiesterase inhibitor. It is an analog of sildenafil (Viagra) which has been detected in numerous different brands of supposedly "herbal" aphrodisiac products sold to boost libido and alleviate erectile dysfunction.
A range of designer analogs of licensed PDE5 inhibitors such as sildenafil and vardenafil have been detected in recent years in over-the-counter herbal aphrodisiac products, in an apparent attempt to circumvent both the legal restrictions on sale of erectile dysfunction drugs, which are prescription-only medicines in most Western countries, and the patent protection which allows sale of these drugs by competitors only with permission from the patent holders (typically, under a license from the inventors). These compounds have been demonstrated to display PDE5 inhibitory activity in vitro and presumably have similar effects when consumed, but have undergone no formal testing in either humans or animals, and as such may represent significant health risks to consumers of these products due to their unknown safety profile. Some attempts have been made to ban these drugs as unlicensed medicines, but progress has been slow so far, as even in those jurisdictions which have laws targeting designer drugs, the laws are drafted to ban analogs of illegal drugs of abuse, rather than analogs of prescription medicines. However, at least one court case has resulted in a product being taken off the market.

CRL-40,941

CRL-40,941 (Fladrafinil) is a mild central nervous system stimulant drug closely related to adrafinil and modafinil. It is the bis(p-fluoro) ring-substituted derivative of adrafinil and has similar effects in animal tests and human trials. The fluorine substitution increases the potency to around twice that of adrafinil. CRL-40,941 was found to produce anti-aggressive effects in animals, which adrafinil does not produce.
As of late 2013 CRL-40,941 has been seen on the recreational drug markets.

2-NE1 (APICA)

SDB-001 (2NE1, APICA, N-(1-adamantyl)-1-pentyl-1H-indole-3-carboxamide) is a drug that acts as a potent agonist for the cannabinoid receptors. It had never previously been reported in the scientific or patent literature, and was first identified by laboratories in Japan in March 2012 as an ingredient in synthetic cannabis smoking blends, along with a related compound APINACA (sold as "AKB48"). Structurally it closely resembles cannabinoid compounds from patent WO 2003/035005

but with an indole core instead of indazole, and a simple pentyl chain on the indole 1-position. Pharmacological testing determined SDB-001 to have an IC50 of 175nM at CB1, only slightly less potent than JWH-018 which had an IC50 of 169nM, but over four times more tightly binding than AKB48, which had an IC50 of 824nM. The first published synthesis and pharmacological evaluation of SDB-001 revealed that it acts as a full agonist at CB1 (EC50 = 34 nM) and CB2 receptors (EC50 = 29 nM). Furthermore, SDB-001 possesses cannabis-like effects in rats, and appears to be less potent than JWH-018 but more potent than THC.

AMT

The name of this research material is alpha methyl tryptamine. AMT belongs to a class of research materials known as’ serotonin agonists’  as well as the class ‘triple releasing agents’  and is a both an hallucinogen  and sympathomimetric amine. AMT has also been shown to possess MAOI (monoamine oxidase inhibition) at higher doses.
AMT is available is available in its pure powder form and is the freebase of the compound.